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  2. Spin column-based nucleic acid purification - Wikipedia

    en.wikipedia.org/wiki/Spin_column-based_nucleic...

    The different stages of the method are lyse, bind, wash, and elute. [1] [2] More specifically, this entails the lysis of target cells to release nucleic acids, selective binding of nucleic acid to a silica membrane, washing away particulates and inhibitors that are not bound to the silica membrane, and elution of the nucleic acid, with the end result being purified nucleic acid in an aqueous ...

  3. Gel electrophoresis - Wikipedia

    en.wikipedia.org/wiki/Gel_electrophoresis

    The graph to the right shows the nonlinear relationship between the size of the DNA fragment and the distance migrated. Gel electrophoresis is a process where an electric current is applied to DNA samples creating fragments that can be used for comparison between DNA samples. DNA is extracted. Isolation and amplification of DNA.

  4. SB buffer - Wikipedia

    en.wikipedia.org/wiki/SB_buffer

    Downstream applications, such as isolation of DNA from a gel slice or southern blot analysis, work as expected with sodium borate gels. LB buffer containing lithium borate is similar to sodium borate and has all of its advantages, but permits use of even higher voltages due to the lower conductivity of lithium ions as compared to sodium ions. [1]

  5. DNA separation by silica adsorption - Wikipedia

    en.wikipedia.org/wiki/DNA_separation_by_silica...

    The highest DNA adsorption efficiencies occur in the presence of buffer solution with a pH at or below the pKa of the surface silanol groups. The mechanism behind DNA adsorption onto silica is not fully understood; one possible explanation involves reduction of the silica surface's negative charge due to the high ionic strength of the buffer.

  6. AncestryDNA kits are just $39 with this early Black Friday ...

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    AncestryDNA kits are incredibly fun to do, and if you haven't gotten one yet, they're only $39 right now. AncestryDNA kits are just $39 with this early Black Friday deal — the lowest price we've ...

  7. Lysis buffer - Wikipedia

    en.wikipedia.org/wiki/Lysis_buffer

    RIPA buffer is a commonly used lysis buffer for immunoprecipitation and general protein extraction from cells and tissues. The buffer can be stored without vanadate at 4 °C for up to 1 year. [10] RIPA buffer releases proteins from cells as well as disrupts most weak interactions between proteins. [9] Recipe: [10] 1% (w/w) Nonidet P-40 (NP-40)

  8. AI could revolutionise DNA evidence – but right now we can't ...

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  9. Molecular machine - Wikipedia

    en.wikipedia.org/wiki/Molecular_machine

    The first example of an artificial molecular machine (AMM) was reported in 1994, featuring a rotaxane with a ring and two different possible binding sites. In 2016 the Nobel Prize in Chemistry was awarded to Jean-Pierre Sauvage , Sir J. Fraser Stoddart , and Bernard L. Feringa for the design and synthesis of molecular machines.