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Tuberculosis has been known by many names from the technical to the familiar. [202] Phthisis (φθίσις) is the Greek word for consumption, an old term for pulmonary tuberculosis; [7] around 460 BCE, Hippocrates described phthisis as a disease of dry seasons. [203] The abbreviation TB is short for tubercle bacillus.
Human bones from the Neolithic show presence of the bacteria. There has also been a claim of evidence of lesions characteristic of tuberculosis in a 500,000-year-old Homo erectus fossil, although this finding is controversial. [4] Results of a genome study reported in 2014 suggest that tuberculosis is newer than previously thought.
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [ 1 ] [ 2 ] First discovered in 1882 by Robert Koch , M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid .
Mycobacterium is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae.This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis (M. tuberculosis) and leprosy in humans.
Mycobacteriaceae is a family of bacteria in the phylum Actinomycetota. [1] [2] Its name is derived from the Mycobacterium genus, which includes pathogens known to cause serious diseases in mammals, including tuberculosis (M. tuberculosis) and leprosy in humans.
Heinrich Hermann Robert Koch (/ k ɒ x / KOKH; [1] [2] German: [ˈʁoːbɛʁt ˈkɔx] ⓘ; 11 December 1843 – 27 May 1910) was a German physician and microbiologist.As the discoverer of the specific causative agents of deadly infectious diseases including tuberculosis, cholera and anthrax, he is regarded as one of the main founders of modern bacteriology.
Since 2018, all members of this species complex are considered synonyms of M. tuberculosis as far as bacterial nomenclature is concerned. The IJSEM article reports that M. africanum, M. bovis, M. caprae, M. pinnipedii are 99.21–99.92% identical to M. tuberculosis on the whole-genome level, failing the criteria to be considered independent ...
Mycobacterium tuberculosis strain H37Rv is the most studied strain of tuberculosis in research laboratories. [1] It was first isolated by Dr. Edward R. Baldwin in 1905. [2] The strain came from a 19 year old patient with chronic pulmonary tuberculosis at the Trudeau Sanatorium in Saranac Lake, New York. [3]