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Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma. [4] This includes multiple myeloma in those who have and have not previously received treatment. [ 3 ]
Bortezomib/dexamethasone is a combination drug against multiple myeloma. [1] When bortezomib is used by the trade name Velcade, the combination is called Vel/Dex (or Vel-Dex or Veldex ). Bortezomib is a proteasome inhibitor and dexamethasone is a corticosteroid .
Bortezomib (Velcade) was approved in 2003. This was the first proteasome inhibitor approved for use in the U.S. Its boron atom binds the catalytic site of the 26S proteasome. [20] Carfilzomib (Kyprolis) was approved by the FDA for relapsed and refractory multiple myeloma in 2012 . [21]
This is an accepted version of this page This is the latest accepted revision, reviewed on 30 January 2025. Classified advertisements website Craigslist Inc. Logo used since 1995 Screenshot of the main page on January 26, 2008 Type of business Private Type of site Classifieds, forums Available in English, French, German, Dutch, Spanish, Italian, Portuguese Founded 1995 ; 30 years ago (1995 ...
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Potassium bromide is used as a veterinary drug, in antiepileptic medication for dogs. Under standard conditions, potassium bromide is a white crystalline powder. It is freely soluble in water; it is not soluble in acetonitrile. In a dilute aqueous solution, potassium bromide tastes sweet, at higher concentrations it tastes bitter, and tastes ...
The levels of lithium needed to dissolve urate in the body, however, were toxic. [129] Because of prevalent theories linking excess uric acid to a range of disorders, including depressive and manic disorders, Carl Lange in Denmark [ 10 ] and William Alexander Hammond in New York City [ 11 ] used lithium to treat mania from the 1870s onwards.
The product is generally considered to be safe to use in household kitchens to control cockroaches and ants. It acts as a stomach poison affecting the insects' metabolism, and the dry powder is abrasive to the insects' exoskeletons. [58] [59] [60] It is in non-specific IRAC group 8D. Boric acid also has the reputation as "the gift that keeps on ...
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