Search results
Results From The WOW.Com Content Network
Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma. [4] This includes multiple myeloma in those who have and have not previously received treatment. [ 3 ]
Bortezomib (Velcade) was approved in 2003. This was the first proteasome inhibitor approved for use in the U.S. Its boron atom binds the catalytic site of the 26S proteasome. [20] Carfilzomib (Kyprolis) was approved by the FDA for relapsed and refractory multiple myeloma in 2012 . [21]
Bortezomib/dexamethasone is a combination drug against multiple myeloma. [1] When bortezomib is used by the trade name Velcade, the combination is called Vel/Dex (or Vel-Dex or Veldex ). Bortezomib is a proteasome inhibitor and dexamethasone is a corticosteroid .
Parachuting or bombing is a method of swallowing drugs by rolling or folding powdered or crushed drugs in a piece of edible paper to ingest while avoiding the unpleasant taste of the chemical. [1]
This often allows a roach to go back to the nest where it soon dies. Cockroaches, being cannibalistic, eat others killed by contact or consumption of boric acid, consuming the powder trapped in the dead roach and killing them, too. [citation needed] Boric acid has also been widely used in the treatment of wood for protection against termites.
The levels of lithium needed to dissolve urate in the body, however, were toxic. [129] Because of prevalent theories linking excess uric acid to a range of disorders, including depressive and manic disorders, Carl Lange in Denmark [ 10 ] and William Alexander Hammond in New York City [ 11 ] used lithium to treat mania from the 1870s onwards.
Diazepam does not possess any chiral centers in its structure, but it does have two conformers.The two conformers mentioned were the 'P'-conformer and 'M'-conformer. Diazepam is an equimolar mixture and it was shown through CD spectra in serum protein solutions, that the 'P'-conformer is preferred by α1-acid glycoprotein b
"Handsome Jack" John Ledford, an outlaw-turned-hotel-owner involved in counterfeiting and horse theft in Kansas and the Indian Territory, is killed in a shootout with a group of U.S. Army soldiers led by scout Lee Stewart and U.S. Marshal Jack Bridges, who claimed to have a warrant for his arrest. [142] Mar 16