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But to first make clear what a bruise is: It’s the result of a broken blood vessel (a.k.a. capillary) which causes a leakage and collection of blood under the skin’s surface, explains Riza ...
When a child has leukemia, the cells do not respond to the signals telling them when to stop and when to produce cells. The bone marrow becomes crowded, resulting in problems producing other blood cells. [4] [5] Common childhood leukemia signs and symptoms include excessive tiredness, easy bruising or bleeding, bone pain and paleness. [6]
Unexplained bruising may be a warning sign of child abuse, domestic abuse, or serious medical problems such as leukemia or meningoccocal infection. Unexplained bruising can also indicate internal bleeding or certain types of cancer. Long-term glucocorticoid therapy can cause easy bruising.
SSSS is a clinical diagnosis. This is sometimes confirmed by isolation of S. aureus from blood, mucous membranes, or skin biopsy; however, these are often negative. Skin biopsy may show separation of the superficial layer of the epidermis (intraepidermal separation), differentiating SSSS from TEN, wherein the separation occurs at the dermo-epidermal junction (subepidermal separation).
Signs of ITP include the spontaneous formation of bruises and petechiae (tiny bruises), especially on the extremities. Additionally, bleeding from the nostrils and/or gums, as well as menorrhagia (excessive menstrual bleeding), may occur if the platelet count falls below 20,000 per μL. [ 4 ]
The most common symptoms in children are easy bruising, pale skin, fever, and an enlarged spleen or liver. [35] Damage to the bone marrow, by way of displacing the normal bone marrow cells with higher numbers of immature white blood cells, results in a lack of blood platelets, which are important in the blood clotting process.
Opzelura showed statistically significant improvement in the chronic skin condition, atopic dermatitis, on a disease severity scale compared to patients treated with non-medicated cream. It ...
A medical sign is an objective observable indication of a disease, injury, or medical condition that may be detected during a physical examination. [7] These signs may be visible, such as a rash or bruise, or otherwise detectable such as by using a stethoscope or taking blood pressure. Medical signs, along with symptoms, help in forming a ...