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They can be found at a depth of 900 μm in human fingertips. [4] In hairy skin, Merkel nerve endings are clustered into specialized epithelial structures called "touch domes" or "hair disks". Merkel receptors are also located in the mammary glands. Wherever they are found, the epithelium is arranged to optimize the transfer of pressure to the ...
Merkel cells, also known as Merkel–Ranvier cells or tactile epithelial cells, are oval-shaped mechanoreceptors essential for light touch sensation and found in the skin of vertebrates. They are abundant in highly sensitive skin like that of the fingertips in humans , and make synaptic contacts with somatosensory afferent nerve fibers .
A mechanoreceptor, also called mechanoceptor, is a sensory receptor that responds to mechanical pressure or distortion. Mechanoreceptors are located on sensory neurons that convert mechanical pressure into electrical signals that, in animals, are sent to the central nervous system.
Pallesthesia (\ˌpal-es-ˈthē-zh(ē-)ə\), or vibratory sensation, is the ability to perceive vibration. [1] [2] This sensation, often conducted through skin and bone, is usually generated by mechanoreceptors such as Pacinian corpuscles, Merkel disk receptors, and tactile corpuscles. [1]
Sexual reproduction is also a form of imperfect self-replication and thus imperfect self-perpetuation because of recombination and mutation. Organisms are not like self-replicating machine but amass random modifications from generation to generation. The property of self-perpetuation in the strict sense thus only applies to life itself.
The formation of the neural tube from the ectoderm is called neurulation. The ventral part of the neural tube is called the basal plate; the dorsal part is called the alar plate. The hollow interior is called the neural canal, and the open ends of the neural tube, called the neuropores, close off. [13]
The system relied heavily on use of a mouse before it was common to have one and was an attempt to make the desktop operating system relatively affordable, according to BYTE Magazine.
Self-actualization was an essential component to Maslow's Hierarchy of Needs, but differed from Goldstein's original concept. Maslow described self-actualization as realizing one's full potential and seeking personal growth. Maslow felt that self-actualization would only be met if all fundamental needs had been satisfied first. [14]