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The AR antagonism of spironolactone mostly underlies its antiandrogenic activity and is the major mechanism responsible for its therapeutic benefits in the treatment of androgen-dependent conditions like acne, hirsutism, and pattern hair loss and its usefulness in hormone therapy for transgender women.
Several hormones — such as insulin, leptin, ghrelin, cortisol and thyroid hormones — have significant influence over metabolism, appetite and fat storage within the body. And imbalanced ...
Response to treatment generally requires 1 to 3 months in the case of acne and up to 6 months in the case of hirsutism. [67] Ongoing therapy is generally required to avoid relapse of symptoms. [67] Spironolactone is commonly used in the treatment of hirsutism in women, and is considered to be a first-line antiandrogen for this indication. [68]
Cortisol is a steroid hormone in the glucocorticoid class of hormones and a stress hormone. When used as medication, it is known as hydrocortisone . It is produced in many animals, mainly by the zona fasciculata of the adrenal cortex in an adrenal gland . [ 1 ]
Cortisol, known as the "stress hormone," influences how the body handles stress and plays a vital in keeping the body healthy. ... About 70% of people with Cushing syndrome are women or people ...
Cortisol is the body's main stress hormone, according to WebMD. It serves many functions, including regulating blood pressure and blood sugar, controlling your sleep cycle, keeping inflammation ...
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