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The American Cancer Society also stated that "natural" and "bioidentical" hormones present the same risks as synthetic hormone replacement therapy such as heart disease, blood clots, strokes and an increased risk of breast cancer with long-term use. [52]
This disruption can lead to miscarriages, fertility problems, and irregular ovulation. Hormone imbalances in females caused by xenohormones caused health issues like thyroid cancer and polycystic ovary syndrome. There is also an increased risk on breast cancer or breast related disorders depending onto length of exposure to xenohormones.
A nonsteroidal estrogen is an estrogen with a nonsteroidal chemical structure. [1] The most well-known example is the stilbestrol estrogen diethylstilbestrol (DES). [1] [2] Although nonsteroidal estrogens formerly had an important place in medicine, they have gradually fallen out of favor following the discovery of toxicities associated with high-dose DES starting in the early 1970s, and are ...
Some women with a high risk of breast cancer can be prescribed tamoxifen; the estrogen-blocking drug is used to treat breast cancer at high doses, but it can also be used at lower doses to reduce ...
These investigational uses include menopausal hormone therapy to treat symptoms such as vaginal atrophy, hot flashes, and bone loss and the treatment of breast cancer and prostate cancer. [2] [3] [7] [8] It is taken by mouth. [2] [3]
Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.
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