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Moreover, breast cancer risk is heightened following use of the combined oral contraceptive pill and combined hormone replacement therapy. [4] Armed with this evidence that endogenous and exogenous changes in estrogen and progesterone levels modulate the risk of breast cancer, it is apparent that hormones can play a key role in breast cancer.
The American Cancer Society also stated that "natural" and "bioidentical" hormones present the same risks as synthetic hormone replacement therapy such as heart disease, blood clots, strokes and an increased risk of breast cancer with long-term use. [52]
[1] [36] [37] Additionally, other epidemiological studies found that consumption of soy estrogens is safe for patients with breast cancer, and that it may decrease mortality and recurrence rates. [ 1 ] [ 38 ] [ 39 ] It remains unclear if phytoestrogens can minimize some of the deleterious effects of low estrogen levels ( hypoestrogenism ...
Xenoestrogens are a type of xenohormone that imitates estrogen.They can be either synthetic or natural chemical compounds.Synthetic xenoestrogens include some widely used industrial compounds, such as PCBs, BPA, and phthalates, which have estrogenic effects on a living organism even though they differ chemically from the estrogenic substances produced internally by the endocrine system of any ...
Antihormone therapy is a type of hormone therapy that suppresses selected hormones or their effects, in contrast with hormone replacement therapy, which encourages hormone activity. The suppression of certain hormones can benefit patients with certain cancers because certain hormones prompt or help the growth of a tumor . [ 1 ]
Natural pregnancy before the age of 20 has been associated with a 50% lifetime reduction in the risk of breast cancer. [56] Pseudopregnancy has been found to produce decreases in risk of mammary gland tumors in rodents similar to those of natural pregnancy, implicating high levels of estrogen and progesterone in this effect.
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