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2. Prostate cancer screening - Wikipedia

   en.wikipedia.org/wiki/Prostate_cancer_screening

   Prostate cancer screening is the screening process used to detect undiagnosed prostate cancer in men without signs or symptoms. [1] [2] When abnormal prostate tissue or cancer is found early, it may be easier to treat and cure, but it is unclear if early detection reduces mortality rates.

3. Prostate-specific antigen - Wikipedia

   en.wikipedia.org/wiki/Prostate-specific_antigen

   Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene.PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland in men and the paraurethral glands in women.

4. Prostate biopsy - Wikipedia

   en.wikipedia.org/wiki/Prostate_biopsy

   PSA screening is controversial as PSA may become elevated due to non-cancerous conditions such as benign prostatic hyperplasia (BPH), by infection, or by manipulation of the prostate during surgery or catheterization. Additionally many prostate cancers detected by screening develop so slowly that they would not cause problems during a man's ...

5. Prostate cancer - Wikipedia

   en.wikipedia.org/wiki/Prostate_cancer

   Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder.Abnormal growth of the prostate tissue is usually detected through screening tests, typically blood tests that check for prostate-specific antigen (PSA) levels.

6. Rectal examination - Wikipedia

   en.wikipedia.org/wiki/Rectal_examination

   In men aged 55–69 who have been counseled on the known harms and potential benefits of prostate cancer screening, the U.S. Preventive Service Task Force May 2018 statement states, "The use of digital rectal examination as a screening modality is not recommended because there is a lack of evidence on the benefits."

7. Active surveillance of prostate cancer - Wikipedia

   en.wikipedia.org/wiki/Active_surveillance_of...

   PSA based screening and treatment of prostate cancer at a localized stage can prevent prostate cancer death for some men. [ 7 ] [ 10 ] However, if curative intervention is the downstream consequence of every screen detected prostate cancer, a large proportion of men will undergo unnecessary treatment and experience functional declines in ...