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Ankylosing spondylitis (AS) is a systemic rheumatic disease, meaning it affects the entire body. 1–2% of individuals with the HLA-B27 genotype develop the disease. [17] Tumor necrosis factor-alpha (TNF α) and interleukin 1 (IL-1) are also implicated in ankylosing spondylitis.
Compared to expectations, women with ankylosing spondylitis were less likely to have had children. [31] People with ankylosing spondylitis experience up to 50% more sick leave episodes, an overall 8% loss of productivity, and a thrice higher rate of disability than the general population.
The term itself is an umbrella term characterizing a diverse disease family united by shared clinical and genetic features, such as the involvement of the axial skeleton. [2] The 2009 introduced term axial spondyloarthritis is a preferred term nowadays and substitutes the old term ankylosing spondylitis. [3]
Ankylosing spondylitis (AS) is a form of arthritis that primarily affects the spine, although other joints can become involved. It causes inflammation of the spinal joints (vertebrae) that can lead to severe, chronic pain and discomfort.
Ankylosing spondylitis is a type of arthritis in which there is long-term inflammation of the joints of the spine. [2] Other forms of arthritis may sometimes also lead to ankylosis, including rheumatoid arthritis and reactive arthritis; Osteoarthritis usually confers osteophyte formation, which may eventually fuse across joints. Osteoarthritis ...
The 31-year-old frontman of the Grammy-winning band is also campaigning to bring awareness to the painful and hidden disease that is ankylosing spondylitis (AS), which he was diagnosed with in his ...
When involving inflammation, it can be called spondylitis. In contrast, a spondyloarthropathy is a condition involving the vertebral joints, but many conditions involve both spondylopathy and spondyloarthropathy. Examples include ankylosing spondylitis and spondylosis.
The BASDAI or Bath Ankylosing Spondylitis Disease Activity Index is a validated diagnostic test which allows a physician, usually a rheumatologist, to determine the effectiveness of a current drug therapy, or the need to institute a new drug therapy for the treatment of Ankylosing spondylitis (AS).
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