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According to the Filarial Genome Project being done by The Special Programme for Research and Training in Tropical Diseases, the Brugia malayi MIF gene is expressed in all life-cycle stages of the parasite, and results suggest that B. malayi MIF may interact with the human immune system during the course of infection by altering the function of ...
Brugia is a genus for a group of small roundworms. They are among roundworms that cause the parasitic disease filariasis . [ 1 ] Specifically, of the three species known, Brugia malayi and Brugia timori cause lymphatic filariasis in humans; and Brugia pahangi and Brugia patei infect domestic cats, dogs and other animals.
Lymphatic filariasis is caused by the worms Wuchereria bancrofti, Brugia malayi, and Brugia timori. These worms occupy the lymphatic system, including the lymph nodes; in chronic cases, these worms can lead to the syndrome of elephantiasis. Loiasis a subcutaneous filariasis is caused by Loa loa (the eye worm).
Brugia malayi, Brugia timori: lymph nodes blood samples tropical regions of Asia arthropods: Dioctophyme renalis infection: Dioctophyme renale: kidneys (typically the right) urine rare ingestion of undercooked or raw freshwater fish Ophidascaris robertsi infection: Ophidascaris robertsi: brain newly discovered infection [12] [13]
The second Wolbachia genome to be determined was of strain wBm, which infects Brugia malayi nematodes . [69] Since the development and release of high-throughput sequencing technologies in the mid-2000s, the number of published Wolbachia genomes has grown significantly, driven by both the decreased cost of sequencing and the expanding interest ...
Whole blood with microfilaria worm, giemsa stain. L. loa worms have a simple structure consisting of a head (which lacks lips), a body, and a blunt tail. The outer body of the worm is composed of a cuticle with three main layers made up of collagen and other compounds which aid in protecting the nematodes while they are inside the digestive system of their host.
Wuchereria bancrofti is a filarial (arthropod-borne) nematode (roundworm) that is the major cause of lymphatic filariasis.It is one of the three parasitic worms, together with Brugia malayi and B. timori, that infect the lymphatic system to cause lymphatic filariasis.
The life cycle of Brugia timori is very similar to that of Wuchereria bancrofti and Brugia malayi, leading to nocturnal periodicity of the disease symptoms. Eosinophilia is common during acute stages of infection. [citation needed] So far Brugia timori has only been found in the Lesser Sunda Islands of Indonesia.