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Chemical structure of an LNA monomer an additional bridge bonds the 2' oxygen and the 4' carbon of the pentose. A locked nucleic acid (LNA), also known as bridged nucleic acid (BNA), [1] and often referred to as inaccessible RNA, is a modified RNA nucleotide in which the ribose moiety is modified with an extra bridge connecting the 2' oxygen and 4' carbon.
The most common RNA analogues are 2'-O-methyl-substituted RNA, locked nucleic acid (LNA) or bridged nucleic acid (BNA), morpholino, [5] [6] and peptide nucleic acid . Although these oligonucleotides have a different backbone sugar—or, in the case of PNA, an amino acid residue in place of the ribose phosphate—they still bind to RNA or DNA ...
To commemorate the occasion, the "B'z 20" campaign was launched that saw two further compilation albums: B'z The Best "Ultra Pleasure" was released on June 18, 2008, and featured the greatest of the band's hits on a two-disc collection in chronological order, along with two all-new modern recordings of older tracks, while B'z The Best "Ultra ...
The 7th Blues was released as a double album in March 1994 after their successful "PLEASURE LIVE-GYM '93 - JAP THE RIPPER" tour. This album was to fully cement B'z evolution from synthesizer-driven pop to mainstream rock.
Gen Z are increasingly choosing trade schools over college to become welders and carpenters because ‘it’s a straight path to a six-figure job’ Orianna Rosa Royle April 4, 2024 at 7:09 AM
A stirred BZ reaction mixture showing changes in color over time. The discovery of the phenomenon is credited to Boris Belousov.In 1951, while trying to find the non-organic analog to the Krebs cycle, he noted that in a mix of potassium bromate, cerium(IV) sulfate, malonic acid, and citric acid in dilute sulfuric acid, the ratio of concentration of the cerium(IV) and cerium(III) ions ...
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