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A chromophobe is a histological structure that does not stain readily, and thus appears relatively pale under the microscope.. Chromophobe cells are one of three cell stain types present in the anterior and intermediate lobes of the pituitary gland, the others being basophils and acidophils.
The anterior pituitary (also called the adenohypophysis or pars anterior) is a major organ of the endocrine system.The anterior pituitary is the glandular, anterior lobe that together with the (posterior pituitary, or the neurohypophysis) makes up the pituitary gland (hypophysis) which, in humans, is located at the base of the brain, protruding off the bottom of the hypothalamus.
The anterior lobe of the pituitary can be divided into the pars tuberalis (pars infundibularis) and pars distalis (pars glandularis) that constitutes ~80% of the gland. The pars intermedia (the intermediate lobe) lies between the pars distalis and the pars tuberalis, and is rudimentary in the human, although in other species it is more ...
In the anterior pituitary, the term "acidophil" is used to describe two different types of cells which stain well with acidic dyes.. somatotrophs, which secrete growth hormone (a peptide hormone)
An anterior pituitary basophil is a type of cell in the anterior pituitary which manufactures hormones.. It is called a basophil because it is basophilic (readily takes up bases), and typically stains a relatively deep blue or purple.
The pars intermedia is one of the three parts of the anterior pituitary. It is a section of tissue sometimes called a middle or intermediate lobe, between the pars distalis, and the posterior pituitary. [1] It is a small region that is largely without blood supply. [2] The cells in the pars intermedia are large and pale.
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Corticotropic cells, (corticotropes or corticotrophs) are basophilic cells in the anterior pituitary that produce pro-opiomelanocortin (POMC) which undergoes cleavage to adrenocorticotropin (ACTH), β-lipotropin (β-LPH), and melanocyte-stimulating hormone (MSH).