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Alpha-1 antitrypsin or α 1-antitrypsin (A1AT, α 1 AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in humans by the SERPINA1 gene.A protease inhibitor, it is also known as alpha 1 –proteinase inhibitor (A1PI) or alpha 1-antiproteinase (A1AP) because it inhibits various proteases (not just trypsin). [5]
Alpha-1 antitrypsin deficiency (A1AD or AATD) is a genetic disorder that may result in lung disease or liver disease. [1] Onset of lung problems is typically between 20 and 50 years of age. [ 1 ] This may result in shortness of breath , wheezing , or an increased risk of lung infections .
A number of anti-evolution bills have been introduced in the United States Congress and State legislatures since 2001. Purporting to support academic freedom, supporters have contended that teachers, students, and college professors face intimidation and retaliation when discussing scientific criticisms of evolution, and therefore require protection. [1]
Anti-foundationalism (also called nonfoundationalism) is any philosophy which rejects a foundationalist approach. An anti-foundationalist is one who does not believe that there is some fundamental belief or principle which is the basic ground or foundation of inquiry and knowledge. [1]
anti-LGI-1 encephalitis: Patients with anti-LGI1 encephalitis have limbic encephalitis with amnesia and/or confusion (100%) and seizures (84-92 %) [4] [6] Other reported features include hyponatremia (in 60%), movement disorders (myoclonus/dyskinesia), sleep disorders (hypersomnia, insomnia, REM sleep behavior disorder, sleep reversal) and ...
The anti-globalization movement, or counter-globalization movement, [1] is a social movement critical of economic globalization. The movement is also commonly referred to as the global justice movement , [ 2 ] alter-globalization movement, anti-globalist movement, anti-corporate globalization movement, [ 3 ] or movement against neoliberal ...
Fluciclovine is a [18 F]-tagged synthetic analog of the amino acid L-leucine.[11] [12] FACBC uptake by the tumor is related to functional activity of two amino acid transporters, [13] specifically sodium-dependent system ASC, with a lesser contribution by sodium-independent system L. [12] Although it is handled by the amino acid transporter system, it does not undergo terminally incorporative ...
AsRNA is transcribed from the lagging strand of a gene and is complementary to a specific mRNA or sense transcript. Antisense RNA (asRNA), also referred to as antisense transcript, [1] natural antisense transcript (NAT) [2] [3] [4] or antisense oligonucleotide, [5] is a single stranded RNA that is complementary to a protein coding messenger RNA (mRNA) with which it hybridizes, and thereby ...