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Apitherapy is a branch of alternative medicine that uses honey bee products, including honey, pollen, propolis, royal jelly and bee venom. There has been no scientific or clinical evidence for the efficacy or safety of apitherapy treatments. [1] [2] Bee venom can cause minor or major reactions, including allergic responses, anaphylaxis or death.
Bee venom is a complex mixture of proteins and smaller molecules. The main component is melittin, which amounts to 52% of venom peptides [2] One of the main allergens is phospholipase A 2, which amounts to 12% and is an enzyme that catalyzes the hydrolysis of phospholipids, causing degradation of cell membranes. [3]
The title page of Beck's Bee Venom Therapy, 1935. Bodog Felix Beck (6 August 1868 – 1 January 1942) was a Hungarian-born American physician who specialized in the treatment of arthritic and rheumatoid conditions using bee venom and who coined the term "bee venom therapy". There are no studies proving the ability of bee venom to cure any ailment.
Bee venom is obtained by stimulating the bee with an electric current that incite them to sting, releasing a drop of poison onto a glass slide. The crystallized venom can be collected and processed. In order to get 1 gram of dry venom, it is necessary to collect the apitoxin of 10,000 to 15,000 bees. [1] [2]
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The fangs deliver a weak venom and simultaneously crush the insect. The Sydney funnel-web spider is a relative with a much more potent neurotoxic venom. Trapdoor spiders, many of which resemble tarantulas but are shinier and less hairy, also have large fangs that deliver painful bites, but have very mild venom.
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