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The first DPP-4 inhibitors were reversible inhibitors and came with bad side effects because of low selectivity. Researchers suspected that inhibitors with short half-lives would be preferred in order to minimize possible side effects. However, since clinical trials showed the
Hair loss is a well-known side effect of many chemotherapy drugs used to treat certain forms of cancer. Similar to other toxins that cause hair loss, hair loss from cancer medications usually isn ...
DPP-4 inhibitors and GLP-1. Inhibitors of dipeptidyl peptidase 4 (DPP-4 inhibitors or gliptins) are a class of oral hypoglycemics that block the enzyme dipeptidyl peptidase-4 (DPP-4). They can be used to treat diabetes mellitus type 2. The first agent of the class – sitagliptin – was approved by the FDA in 2006. [1]
Serious side effects may include angioedema, pancreatitis, joint pain. [ 10 ] [ 8 ] Use in pregnancy and breastfeeding is not recommended. [ 10 ] Linagliptin is a dipeptidyl peptidase-4 inhibitor [ 8 ] that works by increasing the production of insulin and decreasing the production of glucagon by the pancreas .
Side effects from DHT blockers used in hair loss prevention shampoos are also uncommon. Some ingredients may cause irritation, dry skin, itchy skin or other similarly minor effects.
When it comes to injectibal drugs like Ozempic and Wegovy, there are some broad side effects that apply to all injectibals — like swelling, redness or other discomfort at the injection site ...