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The reticulocytes are the cells with the dark blue dots and curved linear structures (reticulum) in the cytoplasm. The normal fraction of reticulocytes in the blood depends on the clinical situation but is usually 0.5% to 2.5% in adults and 2% to 6% in infants. A reticulocyte percentage that is higher than "normal" can be a sign of anemia, but ...
The reticulocyte production index (RPI), also called a corrected reticulocyte count (CRC), is a calculated value used in the diagnosis of anemia. This calculation is necessary because the raw reticulocyte count is misleading in anemic patients. The problem arises because the reticulocyte count is not really a count but rather a percentage: it ...
Nucleated red blood cell. A human peripheral blood smear; NRBCs are visible as larger cells with dark centers. A nucleated red blood cell (NRBC), also known by several other names, is a red blood cell that contains a cell nucleus. Almost all vertebrate organisms have hemoglobin -containing cells in their blood, and with the exception of mammals ...
003642. LOINC. Codes for CBC, e.g., 57021-8. HCPCS-L2. G0306. A complete blood count (CBC), also known as a full blood count (FBC), is a set of medical laboratory tests that provide information about the cells in a person's blood. The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin ...
Erythropoiesis is the development of mature red blood cells from erythropoietic stem cells. The first cell that is morphologically recognizable in the red cell pathway is the proerythroblast. In the basophilic erythroblast, the nucleus becomes somewhat smaller, exhibiting a coarser appearance, and the cytoplasm becomes more basophilic owing to ...
The reticulocyte production index (RPI) or corrected reticulocyte count (CRC) represents the true significance of the absolute reticulocyte count to provide some reflection of erythropoietic demand and supply. The immature reticulocyte fraction (IRF) goes a step further to cast more light on the same question. [citation needed]
Polychromasia is a disorder where there is an abnormally high number of immature red blood cells found in the bloodstream as a result of being prematurely released from the bone marrow during blood formation (poly - refers to many, and -chromasia means color.) These cells are often shades of grayish-blue. Polychromasia is usually a sign of bone ...
Reticulocytosis is a condition where there is an increase in reticulocytes, immature red blood cells. It is commonly seen in anemia. They are seen on blood films when the bone marrow is highly active in an attempt to replace red blood cell loss such as in haemolytic anaemia or haemorrhage. [1][additional citation (s) needed]