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The principal phytochemicals are polyphenols in the leaves, stems, and roots of some Scutellaria species, including baicalin, baicalein, wogonin, and oroxylin A. [5] [6] [7] Other constituents include lateriflorin, melatonin, serotonin, viscidulin III-2’-O-glucoside, Chyrin-6-C-ara-glc, trans-verbascoside, viscidulin, trans-martynoside, oroxylin A-7-O-glc, wogonoside, chitin, and scutellarin ...
Scutellaria galericulata. Scutellaria galericulata, the common skullcap, marsh skullcap[3] or hooded skullcap, is a hardy perennial herb native to northern areas of the Northern Hemisphere, including Europe, Asia, and almost all of Canada. It is a member of the mint family. The form is upright and is usually 20-45 centimeters in height, [4 ...
Serotonin–norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressant medications used to treat major depressive disorder (MDD), anxiety disorders, social phobia, chronic neuropathic pain, fibromyalgia syndrome (FMS), and menopausal symptoms. Off-label uses include treatments for attention-deficit hyperactivity disorder (ADHD ...
A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT). Reuptake inhibition is achieved when extracellular dopamine not absorbed by the postsynaptic neuron is blocked from re-entering the presynaptic neuron.
Generalized anxiety disorder (GAD) is a mental and behavioral disorder, [5] specifically an anxiety disorder characterized by excessive, uncontrollable and often irrational worry about events or activities. [6] Worry often interferes with daily functioning, and individuals with GAD are often overly concerned about everyday matters such as ...
Anxiety disorders are the most common type of mental disorder. They affect nearly 30% of adults at some point in their lives, with an estimated 4% of the global population currently experiencing an anxiety disorder. However, anxiety disorders are treatable, and a number of effective treatments are available. [ 9 ]
Scutellaria is a genus of flowering plants in the mint family, Lamiaceae. They are known commonly as skullcaps. [2] The generic name is derived from the Latin scutella, meaning "a small dish, tray or platter", [3] or "little dish", [4] referring to the shape of the calyx. [4] The common name alludes to the resemblance of the same structure to ...
Meprobamate—marketed as Miltown by Wallace Laboratories and Equanil by Wyeth, among others—is a carbamate derivative used as an anxiolytic drug. It was the best-selling minor tranquilizer for a time, but has largely been replaced by the benzodiazepines due to their wider therapeutic index (lower risk of toxicity at therapeutically prescribed doses) and lower incidence of serious side effects.