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Hoffmann syndrome is a rare form of hypothyroid myopathy and is not to be confused with Werdnig-Hoffmann disease (a type of spinal muscular atrophy). It was first documented in 1897 by Johann Hoffmann . [ 1 ]
Thyrotoxic symptoms are usually mild and in some individuals, the hypothyroid phase is the only symptomatic phase. [4] [5] [7] In the hypothyroid phase, patient may experience cold intolerance, fatigue, weight gain, or depression. The hypothyroidism may or may not resolve spontaneously. [5]
Thyroid diseases are highly prevalent worldwide, [10] [11] [12] and treatment varies based on the disorder. Levothyroxine is the mainstay of treatment for people with hypothyroidism, [13] while people with hyperthyroidism caused by Graves' disease can be managed with iodine therapy, antithyroid medication, or surgical removal of the thyroid ...
Chest discomfort or pain. Severe fatigue and body aches. Swelling or hives. Rapid heart rate. Change in urine color, odor, or frequency. You Might Also Like. The Best Hair Growth Shampoos for Men ...
Several reasons have been identified as to why prescriptions changed from desiccated thyroid treatment. Although thyroid extract was useful and usually effective, some patients continued to complain of fatigue, weight gain, or other symptoms. Dosing until the 1960s was often a matter of prolonged adjustment trials. [19]
The secular trends of hypothyroidism reveal how the disease has changed over the course of time given changes in technology and treatment options. Even though ultrasound technology and treatment options have improved, the incidence of hypothyroidism has increased according to data focused on the US and Europe.
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