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  2. Your Guide to the 6 Most Common Types of Depression ... - AOL

    www.aol.com/6-types-depression-medications...

    Tricyclic antidepressants (TCAs) ... fibromyalgia and chronic musculoskeletal pain. It’s also prescribed off-label for stress urinary incontinence and chemotherapy-induced peripheral neuropathy ...

  3. Tricyclic antidepressant - Wikipedia

    en.wikipedia.org/wiki/Tricyclic_antidepressant

    The TCAs show efficacy in the clinical treatment of a number of different types of chronic pain, notably neuralgia or neuropathic pain and fibromyalgia. [ 17 ] [ 18 ] The precise mechanism of action in explanation of their analgesic efficacy is unclear, but it is thought that they indirectly modulate the opioid system in the brain downstream ...

  4. Amitriptyline - Wikipedia

    en.wikipedia.org/wiki/Amitriptyline

    Amitriptyline, sold under the brand name Elavil among others, is a tricyclic antidepressant primarily used to treat major depressive disorder, and a variety of pain syndromes such as neuropathic pain, fibromyalgia, migraine and tension headaches. [12]

  5. Milnacipran - Wikipedia

    en.wikipedia.org/wiki/Milnacipran

    During its development for fibromyalgia, milnacipran was evaluated utilizing a composite responder approach.To be considered as a responder for the composite ‘treatment of fibromyalgia’ endpoint, each patient had to show concurrent and clinically meaningful improvements in pain, physical function, and global impression of disease status.

  6. The Most Common Antidepressants (& How to Get Them) - AOL

    www.aol.com/most-common-antidepressants-them...

    Unlike other antidepressants, bupropion is known to cause fewer and less severe adverse symptoms, like drowsiness, weight loss, weight gain and intimate dysfunction.

  7. Duloxetine - Wikipedia

    en.wikipedia.org/wiki/Duloxetine

    Duloxetine, tricyclic antidepressants, and anticonvulsants have similar tolerability while opioids cause more side effects. [34] Another review in Prescrire International considered the moderate pain relief achieved with duloxetine to be clinically insignificant and the results of the clinical trials unconvincing.

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