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2. Nicotine - Wikipedia

   en.wikipedia.org/wiki/Nicotine

   Nicotine has a half-life of 1–2 hours. Cotinine is an active metabolite of nicotine that remains in the blood with a half-life of 18–20 hours, making it easier to analyze. [151] Nicotine is metabolized in the liver by cytochrome P450 enzymes (mostly CYP2A6, and also by CYP2B6) and FMO3, which selectively metabolizes (S)-nicotine.

3. For young users, tobacco packets like Zyn are a nicotine ...

   www.aol.com/news/young-users-tobacco-packets-zyn...

   For context, the nicotine ingested from a 6 milligram Zyn pouch would be equal to smoking about three packs of cigarettes or one and a half e-cigarette pods of 2% vape juice per day according to ...

4. Nicotine poisoning - Wikipedia

   en.wikipedia.org/wiki/Nicotine_poisoning

   The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...

5. Smokeless tobacco - Wikipedia

   en.wikipedia.org/wiki/Smokeless_tobacco

   Smokeless tobacco products are produced in various forms, such as chewing tobacco, snuff, snus, and dissolvable tobacco products. [2] Smokeless tobacco is widely used in South Asia and this accounts for about 80% of global consumption. [3] All smokeless tobacco products contain nicotine [4] and are therefore highly addictive. [5]

6. Health effects of tobacco - Wikipedia

   en.wikipedia.org/wiki/Health_effects_of_tobacco

   Nicotine is a highly addictive psychoactive chemical. When tobacco is smoked, most of the nicotine is pyrolyzed; a dose sufficient to cause mild somatic dependency and mild to strong psychological dependency remains. The amount of nicotine absorbed by the body from smoking depends on many factors, including the type of tobacco, whether the ...

7. Altria Group (MO) Q4 2024 Earnings Call Transcript - AOL

   www.aol.com/altria-group-mo-q4-2024-203021439.html

   For the total nicotine space, industry equivalized nicotine volumes increased for the second consecutive year and grew by approximately 2% over the past five years on a compounded annual basis.

8. Nicotine salt - Wikipedia

   en.wikipedia.org/wiki/Nicotine_salt

   A nicotine base and a weak acid such as benzoic acid or levulinic acid is used to form a nicotine salt. [1] Across a sample of 23 nicotine salts available for public purchase, the three most common acids used in the formation of nicotine salts were lactic acid, benzoic acid and levulinic acid. [8]

9. Nicotiana tabacum - Wikipedia

   en.wikipedia.org/wiki/Nicotiana_tabacum

   The concentration of nicotine increases with the age of the plant. Tobacco leaves contain 2 to 8% nicotine combined as malate or citrate. The distribution of the nicotine in the mature plant is widely variable: 64% of the total nicotine exists in the leaves, 18% in the stem, 13% in the root, and 5% in the flowers. [citation needed]