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Lighter Side. Politics. Science & Tech. Sports. Weather. 24/7 Help. ... But the American Heart Association warns against taking daily low-dose aspirin without talking to your doctor first.
The toxic effects of salicylates have been described since at least 1877. [5] In 2004, more than 20,000 cases with 43 deaths were reported in the United States. [1] About 1% of those with an acute overdose die, while chronic overdoses may have severe outcomes. [3] Older people are at higher risks of toxicity for any given dose. [5]
This information was studied by the USPSTF when it made its decision to recommend against taking a daily aspirin, along with data from 14 other randomized controlled trials. Based on all of that ...
For some high-risk cardiovascular patients with stents, the often-recommended practice of prolonged taking of aspirin might be ineffective, and in some cases, even harmful, a new study found.
Low-dose aspirin use was also associated with a trend toward lower risk of cardiovascular events, and lower aspirin doses (75 or 81 mg/day) may optimize efficacy and safety for people requiring aspirin for long-term prevention. [172]
Risk of adverse advents such as bleeding or gastrointestinal side effects is relatively high with daily aspirin therapy. Even a 81 mg daily aspirin regimen for cardiovascular benefits has been shown to increase risk of long-term bleeding, [27] so the significantly higher aspirin doses used for maintenance therapy are of some concern. [19]
Older adults are still likely to take a daily, low dose aspirin for the primary prevention of cardiovascular disease, even though doing so carries significant risks. Using aspirin to ward off ...
NSAIDs aside from (low-dose) aspirin are associated with a doubled risk of heart failure in people without a history of cardiac disease. [66] In people with such a history, use of NSAIDs (aside from low-dose aspirin) was associated with a more than 10-fold increase in heart failure. [67]