Search results
Results From The WOW.Com Content Network
The basic structure of 3rd generation cephalosporins. The majority of third generation cephalosporins have the aminothiazole group at position C-7. Different groups are found at the 7-α-position like 7-α-iminohydroxy and 7-α-iminomethoxy groups. Ceftibuten however possesses a 7-α-ethylidene group. This group gives ceftibuten higher ...
Fourth-generation cephalosporins, however, have true broad-spectrum activity. [23] The classification of cephalosporins into "generations" is commonly practised, although the exact categorization is often imprecise. For example, the fourth generation of cephalosporins is not recognized as such in Japan.
5.2 Children (2 months to 12 ... Community-acquired pneumonia: 400 mg twice daily for 14 days; ... Amongst 3rd-generation oral cephalosporins, ...
Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria, with greater activity against both types of organism than third-generation agents. A 2007 meta-analysis suggested when data of trials were combined, mortality was increased in people treated with cefepime compared with other β-lactam antibiotics . [ 1 ]
Cefoperazone is a third-generation cephalosporin antibiotic, marketed by Pfizer under the name Cefobid. It is one of few cephalosporin antibiotics effective in treating Pseudomonas bacterial infections which are otherwise resistant to these antibiotics. It was patented in 1974 and approved for medical use in 1981. [1]
β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.
Cefpodoxime is an oral, third-generation cephalosporin antibiotic available in various generic preparations. It is active against both Gram-positive and Gram-negative organisms with notable exceptions including Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis.
Cefalotin / ˌ s ɛ f ə ˈ l oʊ t ɪ n / or cephalothin / ˌ s ɛ f ə ˈ l oʊ θ ɪ n / is a first-generation cephalosporin antibiotic with broad spectrum antibiotic activity. [1] [2] It was the first cephalosporin marketed (1964) and continues to be widely used. [3]