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Interneurons can be further broken down into two groups: local interneurons and relay interneurons. [4] Local interneurons have short axons and form circuits with nearby neurons to analyze small pieces of information. [5] Relay interneurons have long axons and connect circuits of neurons in one region of the brain with those in other regions ...
Each of these interneuron class can be further divided into diverse subpopulations of neurons with distinct neurotransmitter phenotype, axonal projection and function during locomotion. [38] For example, V2 interneurons are ipsilaterally projecting that can be further classified as excitatory V2a and inhibitory V2b.
Projection fibers consist of efferent and afferent fibers uniting the cortex with the lower parts of the brain and with the spinal cord. In human neuroanatomy, bundles of axons (nerve fibers) called nerve tracts , within the brain, can be categorized by their function into association tracts , projection tracts , and commissural tracts .
About 90% of neurons in the striatum are medium projection neurons, the other 10% are interneurons. [1] In the direct pathway the neurons project directly to the globus pallidus internal (GPi) and the substantia nigra pars reticulata (SNpr).
Neurons are the excitable cells of the brain that function by communicating with other neurons and interneurons (via synapses), in neural circuits and larger brain networks. The two main neuronal classes in the cerebral cortex are excitatory projection neurons (around 70-80%) and inhibitory interneurons (around 20–30%). [2]
The grey matter in the spinal cord consists of interneurons, as well as the cell bodies of projection neurons. Cross-section of a spinal vertebra with the spinal cord in the centre (and grey matter labelled).
The majority of posterior column projection neurons are located in lamina I, however most neurons in this layer are interneurons. [14] The main areas these neurons innervate are the caudal ventrolateral medulla (CVLM), the nucleus of the solitary tract (NTS), the lateral parabrachial area (LPb), the periaqueductal grey matter (PAG), and certain ...
The cholinergic system consists of projection neurons from the pedunculopontine nucleus, laterodorsal tegmental nucleus, and basal forebrain and interneurons from the striatum and nucleus accumbens. It is not yet clear whether acetylcholine as a neuromodulator acts through volume transmission or classical synaptic transmission, as there is ...