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May slow clotting; contraindicated for people with bleeding disorders and before and after surgery. May induce uterine contractions; contraindicated when pregnant or nursing. [21] Pyrrolizidine alkaloids (contained in comfrey, borage, senecio, coltsfoot, and others) Liver damage [5] Reserpine: Rauvolfia serpentina
The natural cycle of spontaneous ovulation occurs in species such as cows. [21] There is a great demand for ovulation to be induced in cattle, as it allows farmers to synchronize their cattle to ovulate at the same time, helping improve the efficiency of dairy farming. [ 22 ]
Side effects in dogs and cats include hypersalivation, diarrhea, loss of appetite, and vomiting. [12] [16] Eight percent of dogs taking maropitant at doses meant to prevent motion sickness vomited right after, likely due to the local effects maropitant had on the gastrointestinal tract. Small amounts of food beforehand can prevent such post ...
The most common form of sterilization in dogs and cats is surgical, spaying in females and castration in males. Non-surgical fertility control can either result in sterilization or temporary contraception and could offer a cheaper way to keep wild dog and cat populations under control. As of 2019, only contraceptives are commercially available.
Clomifene citrate (Clomid is a common brand name) is the medication which is most commonly used to treat anovulation. It is a selective estrogen-receptor modulator, affecting the hypothalamic–pituitary–gonadal axis to respond as if there was an estrogen deficit in the body, in effect increasing the production of follicle-stimulating hormone.
Ovulation occurs about 109 hours after the start of follicle growth. Estrogen peaks at about 11 am on the day of proestrus. Between then and midnight there is a surge in progesterone, luteinizing hormone and follicle-stimulating hormone, and ovulation occurs at about 4 am on the next estrus day. The following day, metestrus, is called early ...