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  2. Amlodipine - Wikipedia

    en.wikipedia.org/wiki/Amlodipine

    Amlodipine works partly by vasodilation (relaxing the arteries and increasing their diameter). [10] It is a long-acting calcium channel blocker of the dihydropyridine type. [10] Amlodipine was patented in 1982, and approved for medical use in 1990. [12] It is on the World Health Organization's List of Essential Medicines. [13]

  3. Calcium channel blocker toxicity - Wikipedia

    en.wikipedia.org/wiki/Calcium_channel_blocker...

    Other potential symptoms include: nausea and vomiting, a decreased level of consciousness, and breathing difficulties. [2] Symptoms usually begin within 6 hours of taking the medication by mouth. [2] With extended release formulations symptoms may not occur for up to a day. [2] Seizures are rare in adults but in children occur more often. [2]

  4. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    In the VALUE trial, the ARB valsartan produced a statistically significant 19% (p=0.02) relative increase in the prespecified secondary end point of myocardial infarction (fatal and non-fatal) compared with amlodipine. [25] The CHARM-alternative trial showed a significant +52% (p=0.025) increase in myocardial infarction with candesartan (versus ...

  5. Calcium channel blocker - Wikipedia

    en.wikipedia.org/wiki/Calcium_channel_blocker

    This can help ameliorate symptoms of ischaemic heart disease such as angina pectoris. Immunohistochemical analysis of L-type calcium channel Cav1.3 (CACNA1D) in human adrenal cortex: Marked immunoreactivity was detected in the zona glomerulosa. In the figure: ZG = zona glomerulosa, ZF = zona fasciculata, AC = adrenal capsule.

  6. Lisinopril/amlodipine - Wikipedia

    en.wikipedia.org/wiki/Lisinopril/amlodipine

    Lisinopril/amlodipine, sold under the brand name Lisonorm among others, is a medication used to treat high blood pressure. [1] It is a combination of lisinopril an ACE inhibitor with amlodipine a calcium channel blocker. [1] It may be used when blood pressure is not well controlled with each of the two agents alone. [4] It is taken by mouth. [1]

  7. Amlodipine/olmesartan - Wikipedia

    en.wikipedia.org/wiki/Amlodipine/olmesartan

    Amlodipine/olmesartan, sold under the brand name Azor, among others is a fixed-dose combination medication used to treat high blood pressure. [5] It contains amlodipine , as the besilate, a dihydropyridine calcium channel blocker , and olmesartan medoxomil , an angiotensin II receptor blocker .

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  9. ACE inhibitor - Wikipedia

    en.wikipedia.org/wiki/ACE_inhibitor

    Symptoms and Treatment: There are few reports of ACE inhibitor overdose in the literature. The most likely manifestations are hypotension, which may be severe, hyperkalemia, hyponatremia and renal impairment with metabolic acidosis. Treatment should be mainly symptomatic and supportive, with volume expansion using normal saline to correct ...