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  2. Montelukast - Wikipedia

    en.wikipedia.org/wiki/Montelukast

    Montelukast is an inhibitor of the drug metabolizing enzyme CYP2C8, part of the cytochrome P450 system. Therefore, it is theoretically possible that the combination of montelukast with a CYP2C8 substrate (e.g. amodiaquine, an anti-malarial drug) could increase the plasma concentrations of the substrate.

  3. Exclusive-US FDA finds widely used asthma drug impacts ... - AOL

    www.aol.com/news/exclusive-us-fda-finds-widely...

    By 2019, the FDA tallied 82 suicides linked to Singulair and its generic versions reported to its adverse-event database since 1998. At least 31 of those reports involved someone age 19 or younger.

  4. Popular asthma drug Singulair could be linked to mental ... - AOL

    www.aol.com/popular-asthma-drug-singulair-could...

    Singulair, originally sold by Merck & Co., is a prescription drug that was launched in 1998 and is used to prevent and treat symptoms of asthma and allergies, according to the Cleveland Clinic, by ...

  5. Zafirlukast - Wikipedia

    en.wikipedia.org/wiki/Zafirlukast

    Zafirlukast is FDA-approved for the prevention and treatment of asthma in adults and children older than 5 years old. [1] Like other leukotriene receptor antagonists, zafirlukast is thought to be useful for the long-term treatment of asthma, but it is generally less effective than inhaled glucocorticoids as monotherapy (which are the standard of care) or long-acting beta-2 agonists in ...

  6. Generic drug - Wikipedia

    en.wikipedia.org/wiki/Generic_drug

    A generic drug is a pharmaceutical drug that contains the same chemical substance as a drug that was originally protected by chemical patents. Generic drugs are allowed for sale after the patents on the original drugs expire.

  7. Ignore the Noise With This Pharma - AOL

    www.aol.com/news/2012-10-29-ignore-the-noise...

    You can sum up Merck's (NYS: MRK) third quarter in three words: These things happen. Sales were down 4% year over year in the third quarter, but the strengthening of the dollar caused a drop in ...