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The remainder of the serum cholesterol after subtracting the HDL is the non-HDL cholesterol. The concentration of these other components, which may cause atheroma, is known as the non-HDL-C. This is now preferred to LDL-C as a secondary marker as it has been shown to be a better predictor and it is more easily calculated. [10]
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
Remnant cholesterol is the cholesterol content of triglyceride-rich lipoproteins, which consist of very low-density lipoproteins and intermediate-density lipoproteins with chylomicron remnants. [ 2 ] [ 5 ] Remnant cholesterol is primarily chylomicron and VLDL, and each remnant particle contains about 40 times more cholesterol than LDL.
Higher levels of total cholesterol increase the risk of cardiovascular disease, particularly coronary heart disease. [38] Levels of LDL or non-HDL cholesterol both predict future coronary heart disease; which is the better predictor is disputed. [39]
Elevated blood lipids, including high triglyceride levels, low HDL (high-density lipoprotein) cholesterol, and high (low-density lipoprotein) LDL cholesterol levels
The chemical reaction is the same as the total cholesterol measurement, except that the enzymes are blocked from acting on non-HDL lipoproteins by the reagent and their own PEG tails. [8] From these three data LDL may be calculated. According to Friedewald's equation: [9] [LDL] = [Total cholesterol] − [HDL] − [Triglycerides] / 5