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The aqueous humour is a transparent water-like fluid similar to blood plasma, but containing low protein concentrations. It is secreted from the ciliary body , a structure supporting the lens of the eyeball . [ 1 ]
Glaucoma is a group of ocular disorders characterized by high intraocular pressure-associated neuropathies. [10] Intraocular pressure depends on the levels of production and resorption of aqueous humor. Because the ciliary body produces aqueous humor, it is the main target of many medications against glaucoma.
The ciliary muscle is an intrinsic muscle of the eye formed as a ring of smooth muscle [3] [4] in the eye's middle layer, the uvea (vascular layer).It controls accommodation for viewing objects at varying distances and regulates the flow of aqueous humor into Schlemm's canal.
The aqueous humour is a clear watery fluid that is contained in two areas: the anterior chamber between the cornea and the iris, and the posterior chamber between the iris and the lens. The lens is suspended to the ciliary body by the suspensory ligament ( zonule of Zinn ), made up of hundreds of fine transparent fibers which transmit muscular ...
Acetazolamide is an inhibitor of carbonic anhydrase.It is used for glaucoma, epilepsy (rarely), idiopathic intracranial hypertension, and altitude sickness. For the reduction of intraocular pressure (IOP), acetazolamide inactivates carbonic anhydrase and interferes with the sodium pump, which decreases aqueous humor formation and thus lowers IOP.
The trabecular meshwork is assisted to a small degree in the drainage of aqueous humour by a second outflow pathway, the uveo-scleral pathway (5-10% of outflow occurs this way). The uveo-scleral pathway is increased with the use of glaucoma drugs such as prostaglandins (e.g., Xalatan, Travatan).
10. Corneal limbus and 11. Sclera; 12. Conjunctiva, 13. Uvea with 14. Iris, 15. Ciliary body. The anterior segment or anterior cavity [1] is the front third of the eye that includes the structures in front of the vitreous humour: the cornea, iris, ciliary body, and lens. [2] [3] Within the anterior segment are two fluid-filled spaces:
The pars plicata is the portion of the ciliary body that is responsible for producing aqueous humor, the fluid of the anterior chamber. [2] The production of too much aqueous humor, or reabsorption that occurs too slowly, can lead to increases in the pressure within the eye .