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The animal extracellular matrix includes the interstitial matrix and the basement membrane. [7] Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. [ 8 ]
A matricellular protein is a dynamically expressed non-structural protein that is present in the extracellular matrix (ECM). [1] [2] Rather than serving as stable structural elements in the ECM, these proteins are rapidly turned over and have regulatory roles. They characteristically contain binding sites for ECM structural proteins and cell ...
[23] [24] As well as influencing apoptosis, HSP60 changes in expression level have been shown to be “useful new biomarkers for diagnostic and prognostic purposes.” [ 23 ] According to Lebret et al., a loss of HSP60 expression “indicates a poor prognosis and the risk of developing tumor infiltration” specifically with bladder carcinomas ...
Extracellular polymeric substances (EPSs) are natural polymers of high molecular weight secreted by microorganisms into their environment. [1] EPSs establish the functional and structural integrity of biofilms , and are considered the fundamental component that determines the physicochemical properties of a biofilm. [ 2 ]
EGF-containing fibulin-like extracellular matrix protein 2 is a protein that in humans is encoded by the EFEMP2 gene. [4] [5] [6]A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during ...
Extracellular DNA acts as a functional extracellular matrix component in the biofilms of several bacterial species. It may act as a recognition factor to regulate the attachment and dispersal of specific cell types in the biofilm; [ 44 ] it may contribute to biofilm formation; [ 45 ] and it may contribute to the biofilm's physical strength and ...
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16854 Ensembl ENSG00000131981 ENSMUSG00000050335 UniProt P17931 P16110 RefSeq (mRNA) NM_001177388 NM_002306 NM_001357678 NM_001145953 NM_010705 RefSeq (protein) NP_002297 NP_001344607 n/a Location (UCSC) Chr 14: 55.12 – 55.15 Mb Chr 14: 47.61 – 47.62 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Galectin-3 is a protein that in humans is encoded by the LGALS3 gene. Galectin-3 is ...