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A retinal ganglion cell (RGC) is a type of neuron located near the inner surface (the ganglion cell layer) of the retina of the eye.It receives visual information from photoreceptors via two intermediate neuron types: bipolar cells and retina amacrine cells.
Retinal ganglion cell axons collectively form the optic nerve, via which they project to the brain. [8] The rod and cone photoreceptors signal their absorption of photons via a decrease in the release of the neurotransmitter glutamate to bipolar cells at its axon terminal. Since the photoreceptor is depolarized in the dark, a high amount of ...
[disputed – discuss] The bipolar cells then transmit the signals from the photoreceptors or the horizontal cells, and pass it on to the ganglion cells directly or indirectly (via amacrine cells). Unlike most neurons, bipolar cells communicate via graded potentials, rather than action potentials.
Bipolar cells convey impulses from photoreceptors (rods and cones) to ganglion cells, [6] which in turn transport the visual signals to the brain through the optic nerve. Bipolar cells come in two varieties, having either an on-center or an off-center receptive field, each with a surround of the opposite sign.
Visual phototransduction is the sensory transduction process of the visual system by which light is detected by photoreceptor cells (rods and cones) in the vertebrate retina.A photon is absorbed by a retinal chromophore (each bound to an opsin), which initiates a signal cascade through several intermediate cells, then through the retinal ganglion cells (RGCs) comprising the optic nerve.
The photoreceptors were identified in 2002 by Samer Hattar, David Berson and colleagues, where they were shown to be melanopsin expressing ganglion cells that possessed an intrinsic light response and projected to a number of brain areas involved in non-image-forming vision.
Retinal precursor cells are biological cells that differentiate into the various cell types of the retina during development. In the vertebrate, these retinal cells differentiate into seven cell types, including retinal ganglion cells , amacrine cells , bipolar cells , horizontal cells , rod photoreceptors , cone photoreceptors , and Müller ...
AII amacrine cells serve the critical role of transferring light signals from rod photoreceptors to the retinal ganglion cells (which contain the axons of the optic nerve). The AII amacrine cells are unique because they work primarily with the vertical transmission of information, meaning they connect the bipolar and ganglion cells.