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Patients present with an acute onset of swelling, pain, erythema, prominent tenderness, warmness and limited range of motion in both ankles. [1] [2] Lower legs and heels may also be involved, however the distal parts of feet and toes are usually spared. Patients may also experience high-graded fever, pitting edema and hypotension.
Lymphedema is most frequently a complication of cancer treatment or parasitic infections, but it can also be seen in a number of genetic disorders. Tissues with lymphedema are at high risk of infection because the lymphatic system has been compromised. [3] Though incurable and progressive, a number of treatments may improve symptoms. [2]
Pain may be the first noticed symptom. [3] People with lipodermatosclerosis have tapering of their legs above the ankles, forming a constricting band resembling an inverted champagne bottle. [ 3 ] [ 5 ] In addition, there may be brownish-red pigmentation and induration .
Milroy's disease is also known as primary or hereditary lymphedema type 1A or early onset lymphedema. It is a very rare disease with only about 200 cases reported in the medical literature. Milroy's disease is an autosomal dominant condition caused by a mutation in the FLT4 gene which encodes the vascular endothelial growth factor receptor 3 ...
Appetite loss has been documented with the presence of inflammation (inflammation-associated anorexia), [6] but it is unclear whether appetite loss seen in patients with lymphangitis leads to weight loss; in cases that develop after lymphedema—which can be upwards of 8.14% of the time [7] —weight gain has actually been documented. [8]
The most typical areas where injuries occur are the back of the feet, the toes, the legs, and the area around a venous ulcer formed in the extremities, although the latter is the rarest of all. [2] These injuries include pachydermia (thickening of the skin), lymphedema (swelling due to lymph vessel blockage), lymphomastic verrucosis and ...
Chronic venous insufficiency (CVI) is a medical condition characterized by blood pooling in the veins, leading to increased pressure and strain on the vein walls. [1] The most common cause of CVI is superficial venous reflux, which often results in the formation of varicose veins, a treatable condition. [2]
Climber's finger is one of the most common climbing injuries within the sport of rock climbing, accounting for about 30% of finger injuries seen in climbers. [1] It is an overuse injury that usually manifests in a swollen middle or ring finger due to a damaged flexor tendon pulley , normally the A2 or A4 pulley.