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A narrow-spectrum antibiotic is an antibiotic that is only able to kill or inhibit limited species of bacteria. [1] Examples of narrow-spectrum antibiotics include fidaxomicin and sarecycline . Advantages
The following is a list of antibiotics. ... May be more narrow-spectrum than vancomycin, resulting in less bowel microbiota alteration. [9] Nausea (11%), vomiting ...
Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class. Antibiotics are listed alphabetically within their class or subclass by their nonproprietary name. If an antibiotic is a combination drug, both ingredients will be listed.
Monobactam antibiotics exhibit no IgE cross-reactivity reactions with penicillin but have shown some cross reactivity with cephalosporins, most notably ceftazidime, which contains an identical side chain as aztreonam. [8] Monobactams can trigger seizures in patients with history of seizures, although the risk is lower than with penicillins.
Sarecycline is a narrow-spectrum antibiotic. [56] [57] Omadacycline: 16+ hours (long) (formerly known as PTK-0796 [58]) received FDA approval on October 2, 2018, for treatment of community-acquired pneumonia [59] and acute skin and skin structure infections. [60]
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These antibiotics are effective principally against Gram-positive cocci. First-generation examples exhibit a narrow spectrum of action and are bactericidal only against the enterococci. Some tissues are not penetrated very well by glycopeptides, and they do not penetrate into the cerebrospinal fluid.