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A narrow-spectrum antibiotic is an antibiotic that is only able to kill or inhibit limited species of bacteria. [1] Examples of narrow-spectrum antibiotics include fidaxomicin and sarecycline . Advantages
Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
Antibiotic spectrum of activity is a component of antibiotic classification. A broad-spectrum antibiotic is active against a wide range of bacteria, [4] whereas a narrow-spectrum antibiotic is effective against specific families of bacteria. [5] An example of a commonly used broad-spectrum antibiotic is ampicillin. [5]
This will usually involve the use of a narrow-spectrum antibiotic. The choice of antibiotic given will also be based on its cost. Identification is critically important as it can reduce the cost and toxicity of the antibiotic therapy and also reduce the possibility of the emergence of antimicrobial resistance. [35]
Gram-negative: Third-generation cephalosporins have a broad spectrum of activity and further increased activity against gram-negative organisms. They may be particularly useful in treating hospital-acquired infections, although increasing levels of extended-spectrum beta-lactamases are reducing the clinical utility of this class of antibiotics.
The Microsoft founder also spoke about how he probably would have been placed on the autism spectrum had he been a child today. “It used to be autism had a fairly narrow definition that was ...
Narrowband signals are signals that occupy a narrow range of frequencies or that have a small fractional bandwidth. [1] In the audio spectrum, narrowband sounds are sounds that occupy a narrow range of frequencies. In telephony, narrowband is usually considered to cover frequencies 300–3400 Hz, i.e. the voiceband.
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