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After an FDA advisory committee said the decongestant phenylephrine, an ingredient found in many oral cold and flu medications, is ineffective, experts weigh in on alternatives.
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
Propylhexedrine should not be used if a MAOI has been used in the past 14 days or is currently in use by a person. [2] Unlike other topical decongestants, propylhexedrine is not required to carry a warning against use in individuals with hypertension. [9] Propylhexedrine is not recommended in individuals younger than six years of age. [10]
Due to its sympathomimetic effects, pseudoephedrine is a vasoconstrictor and pressor agent (increases blood pressure), a positive chronotrope (increases heart rate), and a positive inotrope (increases force of heart contractions). [18] [1] [22] [19] [20] The influence of pseudoephedrine on blood pressure at clinical doses is controversial.
Medications like Vicks Vapo-Rub or topical menthol ointment may also provide symptomatic relief, says Dr. Adalja. In adults and children age 2 and older, use it only on the neck and chest to ease ...
A popular over-the-counter decongestant ingredient doesn’t actually work, according to advisors to the FDA. CVS plans to pull some products containing popular decongestant from shelves.