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As the fetal hypothalamus matures, the activation of the hypothalamic–pituitary–adrenal (HPA) axis initiates labor through two hormonal mechanisms. The end pathway of both mechanisms lead to contractions in the myometrium, a mechanical cause of placental separation, which is due to the sheer force and contractile and involutive changes that occur within the uterus, distorting the placentome.
Childbirth, also known as labour, parturition and delivery, is the completion of pregnancy where one or more babies exits the internal environment of the mother via vaginal delivery or caesarean section. [7]
Uterine smooth muscle mechanisms of relaxation differ significantly from those of other human smooth muscles. [15] Removal of Ca 2+ after contraction induces relaxation of the smooth muscle, and restores the molecular structure of the sarcoplasmic reticulum for the next contractile stimulus.
A spontaneous vaginal delivery (SVD) occurs when a pregnant woman goes into labor without the use of drugs or techniques to induce labor and delivers their baby without forceps, vacuum extraction, or a cesarean section. [1] An induced vaginal delivery is a delivery involving labor induction, where drugs or manual techniques are used to initiate ...
Immune tolerance in pregnancy or maternal immune tolerance is the immune tolerance shown towards the fetus and placenta during pregnancy.This tolerance counters the immune response that would normally result in the rejection of something foreign in the body, as can happen in cases of spontaneous abortion.
This elaborate mechanism of labor, which requires a constant readjustment of the fetal head in relation to the bony pelvis (and which may vary somewhat depending on the shape of the pelvis in question), is completely different from the obstetrical mechanics of the other higher primates whose infants generally drop through the pelvis without any ...
Pain management during childbirth is the partial treatment and a way of reducing any pain that a woman may experience during labor and delivery.The amount of pain a woman feels during labor depends partly on the size and position of her baby, the size of her pelvis, her emotions, the strength of the contractions, and her outlook. [1]
Uterotonics are used both to induce labor and to reduce postpartum hemorrhage. [1] Labor induction in the third trimester of pregnancy may be required due to medical necessity, or may be desired for social reasons. Generally, labor induction is indicated when the risk of carrying the pregnancy outweighs the risk of delivering. These reason ...