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The treatment is usually administered in four week cycles, often for six cycles. MSD and VCR are administered intravenously, while procarbazine and prednisone are pills taken orally. A newer Hodgkin lymphoma treatment is ABVD. C-MOPP involves switching the nitrogen mustard from mechlorethamine to cyclophosphamide.
Hodgkin lymphoma can be sub-classified by histological type. The cell histology in Hodgkin lymphoma is not as important as it is in non-Hodgkin lymphoma: the treatment and prognosis in classic Hodgkin lymphoma usually depends on the stage of disease rather than the histotype. [42]
Treatment-related leukemias are uncommon with ABVD, especially as compared with MOPP. [4] However, one study found a risk of second cancers as high as 28% at 25 years after treatment for Hodgkin lymphoma, although most of the patients in this study were treated with MOPP chemotherapy rather than ABVD. [9]
Stanford V (usually spoken as Stanford Five), is a chemotherapy regimen (with accompanying Radiation therapy) intended as a first-line treatment for Hodgkin lymphoma.The regimen was developed in 1988, with the objective of maintaining a high remission rate while reducing the incidence of acute and long term toxicity, pulmonary damage, and sterility observed in alternative treatment regimens ...
GVD is a chemotherapy regimen, used for salvage treatment of relapsed or refractory Hodgkin disease, including those patients who relapse after stem cell transplantation. [1] The GVD regimen consists of three drugs, from which its name is derived: Gemcitabine; Vinorelbine; and; Doxil, a pegylated liposomal formulation of doxorubicin.
COPP is a chemotherapy regimen for treatment of Hodgkin disease, consisting of concurrent treatment with Cyclophosphamide, Oncovin, Procarbazine and Prednisone.. It contains less procarbazine than MOPP (procarbazine is given only for 10 days in cycle instead of 14), and the very toxic mechlorethamine, which is prone to giving severe neutropenia and to severely heighten the risk of secondary ...
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