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  2. Nucleoside-modified messenger RNA - Wikipedia

    en.wikipedia.org/wiki/Nucleoside-modified...

    This is useful, for example, when used in vaccines, as nanoparticles are taken up by dendritic cells and macrophages, both of which play an important role in activating the immune system. [ 13 ] Furthermore, it may be desirable that the modRNA applied is introduced into specific body cells.

  3. UB-612 - Wikipedia

    en.wikipedia.org/wiki/UB-612

    UB-612 is a COVID-19 vaccine candidate developed by United Biomedical Asia , and Vaxxinity, Inc. [2] It is a peptide vaccine. [3] [4] It is composed of SARS-CoV-2 S1-RBD protein and synthetic peptides representing T cell (Th and CTL) epitopes on the nucleocapsid, spike and membrane proteins. The multitope composition is differentiated from ...

  4. N1-Methylpseudouridine - Wikipedia

    en.wikipedia.org/wiki/N1-methylpseudouridine

    N1-Methylpseudouridine is the methylated derivative of pseudouridine.It is used in in vitro transcription and for the production of RNA vaccines. [3] [4] In vertebrates, it stimulates significantly less activation of the innate immune response compared to uridine, [5] while the translation is stronger.

  5. SM-102 - Wikipedia

    en.wikipedia.org/wiki/SM-102

    SM-102 is a synthetic amino lipid which is used in combination with other lipids to form lipid nanoparticles. [1] These are used for the delivery of mRNA-based vaccines, [2] [3] [4] and in particular SM-102 forms part of the drug delivery system for the Moderna COVID-19 vaccine.

  6. ALC-0315 - Wikipedia

    en.wikipedia.org/wiki/ALC-0315

    The preparation of ALC-0315 was first described in a patent application to lipid nanoparticles by Acuitas Therapeutics in 2017. [6]: 137 The final step is a reductive amination reaction in which 4-aminobutanol is condensed with a lipid aldehyde, using sodium triacetoxyborohydride as the reducing agent to convert the intermediate imines to the amine of the product.

  7. Coronavirus membrane protein - Wikipedia

    en.wikipedia.org/wiki/Coronavirus_membrane_protein

    Illustration of a coronavirus virion in the respiratory mucosa, showing the positions of the four structural proteins and components of the extracellular environment. [15] The M protein is the most abundant protein in coronavirus virions. [8] [5] [4] It is essential for viral replication. [4]

  8. What to know about religious exemptions for the COVID-19 vaccine

    www.aol.com/news/know-religious-exemptions-covid...

    Here's what you should know about claiming religious exemptions as more vaccine mandates are implemented statewide. Skip to main content. 24/7 help. For premium support please call: 800 ...

  9. Janssen COVID-19 vaccine - Wikipedia

    en.wikipedia.org/wiki/Janssen_COVID-19_vaccine

    The Janssen COVID‑19 vaccine, (Ad26.COV2.S) sold under the brand name Jcovden, [1] is a COVID‑19 vaccine that was developed by Janssen Vaccines in Leiden, Netherlands, [24] and its Belgian parent company Janssen Pharmaceuticals, [25] a subsidiary of American company Johnson & Johnson.