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A 2016 analysis of emergency department visits from 2010 to 2013 reported over 36,000 visits annually for chemical burns to the eye, with a median age at presentation of 32 years. [4] By individual year of age, 1- and 2-year-old children have the highest incidence of these injuries, with rates approximately 50% higher than the highest-risk ...
Sodium hydroxide is a dangerous chemical due to its ability to hydrolyze protein. If a dilute solution is spilled on the skin, burns may result if the area is not washed thoroughly and for several minutes with running water. Splashes in the eye can be more serious and can lead to blindness. [40]
Long-term contact lens use can lead to alterations in corneal thickness, stromal thickness, curvature, corneal sensitivity, cell density, and epithelial oxygen uptake. . Other structural changes may include the formation of epithelial vacuoles and microcysts (containing cellular debris), corneal neovascularization, as well as the emergence of polymegethism in the corneal endoth
The prognosis for CSR is generally excellent. While immediate vision loss may be as poor as 20/200 in the affected eye, clinically, over 90% of patients regain 20/25 vision or better within 45 days. [1] Once the fluid has resolved, either spontaneously or through treatment, distortion is reduced and visual acuity improves as the eye heals.
Acute chlorine gas poisoning primarily affects the respiratory system, causing difficulty breathing, cough, irritation of the eyes, nose, and throat, and sometimes skin irritation. Higher exposures can lead to severe lung damage, such as toxic pneumonitis or pulmonary edema , with concentrations around 400 ppm and beyond potentially fatal.
When the cornea dries out it may stick to the eyelid and cause an abrasion when the eye reopens. [11] Exposure keratitis. Chemical injury can occur if cleaning solutions such as povidone-iodine (Betadine), chlorhexidine or alcohol are inadvertently spilt into the eye, for example when the face, neck or shoulder is being prepped for surgery. [4] [1]
[1] [2] Decreased vision may start as early as twelve hours after exposure. [2] Long-term outcomes may include blindness and kidney failure . [ 1 ] Blindness may occur after drinking as little as 10 mL; death may occur after drinking quantities over 15 mL (median 100 mL, varies depending on body weight).
Exposure may also occur through skin or eye contact or by ingesting chlorine-contaminated food or water. Chlorine is a strong oxidizing element causing the hydrogen to split from water in moist tissue, resulting in nascent oxygen and hydrogen chloride that cause corrosive tissue damage.