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Ruffini corpuscles respond to sustained pressure [4] and show very little adaptation. [5] Ruffinian endings are located in the deep layers of the skin, and register mechanical deformation within joints, more specifically angle change, with a specificity of up to 2.75 degrees, as well as continuous pressure states.
The Pacinian corpuscles are located within the deeper layer of the skin, under the skin in the subcutaneous tissues, within muscles, in the periosteum, and other deeper layers of the body. The Merkel disk receptors are located in the superficial epidermis and in hair follicles, while tactile corpuscles are concentrated heavily in the fingertips ...
Lamellar corpuscles, or Pacinian corpuscles or Vater-Pacini corpuscle, are deformation or pressure receptors located in the skin and also in various internal organs. [8] Each is connected to a sensory neuron. Because of its relatively large size, a single lamellar corpuscle can be isolated and its properties studied.
Angelo Ruffini (Pretare of Arquata del Tronto; 1864–1929) was an Italian histologist and embryologist. He studied medicine at the University of Bologna , where beginning in 1894 he taught classes in histology .
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Merkel's Disks - Located on the upper part of the dermis. Slow adapting receptors. Found on the fingertips as well as the eyelids. Meissner's Corpuscles - Located also on the upper part of the dermis. Found on the hairless skin including the lips as well as the eyelids. These are rapid adapting receptors.
Pacinian corpuscles are larger and fewer in number than Meissner's corpuscles, Merkel cells and Ruffini's corpuscles. [7] They may measure up to 2 mm in length, and nearly 1 mm in diameter. [8] They are oval, spherical, or irregularly coiled in shape. Larger ones are visible to the naked eye. [3]
Today, the term "Vater-Pacini corpuscles" is sometimes used to credit the discoveries of both men. [2] These organs are one of several types of mechanoreceptors in the body, some others being Meissner corpuscles (tactile and touch receptors), Ruffini corpuscles (respond to skin stretch and torque), and Krause corpuscles.