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  2. Narcan 101: How to use it, why it works and how to get it - AOL

    www.aol.com/news/narcan-101-why-works-180015261.html

    Narcan — generic name: naloxone — is a medication that reverses opioid overdoses. Here's more on what it is, how it works and where to find Narcan. Narcan — generic name: naloxone — is a ...

  3. What is Narcan and how do you use it? - AOL

    www.aol.com/lifestyle/narcan-173326424.html

    Narcan, also known as Naloxone, is a nasal spray that can combat the life-threatening effects of an opioid overdose. It's needle-free and requires no medical training to use, which makes it ...

  4. Naloxone - Wikipedia

    en.wikipedia.org/wiki/Naloxone

    Naloxone is a non-selective and competitive opioid receptor antagonist. [6] [17] It reverses the depression of the central nervous system and respiratory system caused by opioids. [13] Naloxone was patented in 1961 and approved for opioid overdose in the United States in 1971. [18] [19] It is on the World Health Organization's List of Essential ...

  5. Where to get free Narcan, needles and other help for ... - AOL

    www.aol.com/where-free-narcan-needles-other...

    Here are some places to get free Narcan and training: Care of Southeastern Michigan's Recovery United Community Center in Fraser offers drive-up Narcan training. It also offers training for ...

  6. Inverse agonist - Wikipedia

    en.wikipedia.org/wiki/Inverse_agonist

    The opioid antagonists naloxone and naltrexone act as neutral antagonists of the mu opioid receptors under basal conditions, but as inverse agonists when an opioid such as morphine is bound to the same channel. 6α-naltrexo, 6β-naltrexol, 6β-naloxol, and 6β-naltrexamine acted neutral antagonists regardless of opioid binding and caused ...

  7. Take-home naloxone program - Wikipedia

    en.wikipedia.org/wiki/Take-Home_Naloxone_Program

    Naloxone was created in a laboratory, patented in 1961, and approved by the FDA a decade later. [1] It was first proposed in the 1990s for community-based provisions of take-home naloxone rescue kits (THN) to opioid users, which involved training opioid users, along with their family or friends, in awareness, emergency management, and administration of naloxone. [2]

  8. Narcan is lifesaving in the event of an overdose. Where can ...

    www.aol.com/narcan-lifesaving-event-overdose...

    Narcan is a lifesaving drug but a pack of two doses can cost up to $45 which can be a problem for many people who may need it one day. Narcan is a lifesaving drug but a pack of two doses can cost ...

  9. Coma cocktail - Wikipedia

    en.wikipedia.org/wiki/Coma_cocktail

    Naloxone has well-documented effectiveness; as a matter of fact, 575/609 patients (mainly with heroin overdose) showed improved consciousness and respiration within five minutes of treatment. [1] The major downsides to naloxone are the hypersensitivity from the patient and its reaction with substances contaminating opioids/opiates.