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Estrogen insensitivity syndrome (EIS), or estrogen resistance, is a form of congenital estrogen deficiency or hypoestrogenism [2] which is caused by a defective estrogen receptor (ER) – specifically, the estrogen receptor alpha (ERα) – that results in an inability of estrogen to mediate its biological effects in the body. [3]
Hypoestrogenism, or estrogen deficiency, refers to a lower than normal level of estrogen. It is an umbrella term used to describe estrogen deficiency in various conditions. Estrogen deficiency is also associated with an increased risk of cardiovascular disease, [1] and has been linked to diseases like urinary tract infections [2] and osteoporosis.
Hypogonadism means diminished functional activity of the gonads—the testicles or the ovaries—that may result in diminished production of sex hormones.Low androgen (e.g., testosterone) levels are referred to as hypoandrogenism and low estrogen (e.g., estradiol) as hypoestrogenism.
What's more, estrogen (which remember is a byproduct of T in men), stops osteoclast activity. If your T is low, your estrogen levels will also be low, and you'll have decreased bone density. 13.
Cabergoline treatment may increase orgasmic function, boost intimate desire and treat medical conditions like testosterone deficiency in men. Certain types of intimate dysfunction may also see ...
Common inherited variants in genes that encode enzymes employed in DNA mismatch repair are associated with increased risk of sperm DNA damage and male infertility. [39] As men age there is a consistent decline in semen quality, and this decline appears to be due to DNA damage. [ 40 ]
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