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A systematic review is a scholarly synthesis of the evidence on a clearly presented topic using critical methods to identify, define and assess research on the topic. [1] A systematic review extracts and interprets data from published studies on the topic (in the scientific literature), then analyzes, describes, critically appraises and summarizes interpretations into a refined evidence-based ...
Systematic Reviews is an online-only open access peer-reviewed medical journal published by BioMed Central that focuses on systematic reviews.Articles are either about specific systematic reviews, reporting their protocols, methodologies, findings, follow-up, etc., or else they are about such reviews as a class, discussing the science of systematic reviews.
The PRISMA flow diagram, depicting the flow of information through the different phases of a systematic review. PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) is an evidence-based minimum set of items aimed at helping scientific authors to report a wide array of systematic reviews and meta-analyses, primarily used to assess the benefits and harms of a health care ...
At its core is the collection of Cochrane Reviews, a database of systematic reviews and meta-analyses that summarize and interpret the results of medical research. The Cochrane Library aims to make the results of well-conducted clinical trials readily available and is a key resource in evidence-based medicine .
Systematic reviews may include meta-analysis results. [6] The first edition of the Handbook of Research Synthesis aided the development of various analysis techniques that could be used in systematic review articles, thereby developing this form of literature. [6] Exemplar of Alzheimer's Disease review article
In medical research, an umbrella review is a review of systematic reviews or meta-analyses. [1] [2] [3] They may also be called overviews of reviews, reviews of reviews, summaries of systematic reviews, or syntheses of reviews. [1] Umbrella reviews are among the highest levels of evidence currently available in medicine. [2]
It was developed in response to Archie Cochrane's call for up-to-date, systematic reviews of all relevant randomised controlled trials in the field of healthcare. [11] [12] [13] In 1998, the Cochrane Economics Methods Group (CEMG) was established to facilitate the basing of decisions on health economics, evidence-based medicine, and systematic ...
A systematic review is focused on a specific research question, trying to identify, appraise, select, and synthesize all high-quality research evidence and arguments relevant to that question. A meta-analysis is typically a systematic review using statistical methods to effectively combine the data used on all selected studies to produce a more ...