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Sialolithiasis (also termed salivary calculi, [1] or salivary stones) [1] is a crystallopathy where a calcified mass or sialolith forms within a salivary gland, usually in the duct of the submandibular gland (also termed "Wharton's duct"). Less commonly the parotid gland or rarely the sublingual gland or a minor salivary gland may develop ...
Saliva stagnates and forms a mucus plug behind the stricture during sleep when the salivary output of the parotid is reduced. Then, when salivary secretion is stimulated, the mucus plug becomes stuck in the stricture. [1] The backlog of saliva behind the blockage causes the swelling, and the increased pressure inside the gland causes the pain.
Salivary gland dysfunction affects the flow, amount, or quality of saliva produced. A reduced salivation is termed hyposalivation.Hyposalivation often results in a dry mouth condition called xerostomia, and this can cause tooth decay due to the loss of the protective properties of saliva.
The blockage may be from a salivary stone, a mucous plug, or, more rarely, by a tumor, usually benign. Salivary stones (also called sialolithiasis, or salivary duct calculus) are mainly made of calcium, but do not indicate any kind of calcium disorder. [7] Other causes can be duct stricture (narrowing of the duct), infection or injury.
The two parotid glands are major salivary glands wrapped around the mandibular ramus in humans. [6] These are largest of the salivary glands, secreting saliva to facilitate mastication and swallowing, and amylase to begin the digestion of starches. [7] It is the serous type of gland which secretes alpha-amylase (also known as ptyalin). [8]
Mucoepidermoid carcinoma is a common malignant tumour of the salivary glands and has a low incidence of 4–13%. [13] Adenoid cystic carcinoma is also a common malignant salivary gland lesion and has an incidence of 4–8%. This carcinoma tends to invade nerves and can re-occur post-treatment.
This occurs because of a ruptured salivary gland duct usually caused by local trauma (damage) in the case of mucous extravasation phenomenon and an obstructed or ruptured salivary duct in the case of a mucus retention cyst. The mucocele has a bluish, translucent color, and is more commonly found in children and young adults.
Salivary gland atresia is congenital blockage or absence of the orifice of a major salivary gland duct or part of the duct itself. [1] It is a very rare condition. [1] [2] The submandibular salivary gland duct is usually involved, having failed to cannulate during embryological development. The condition first becomes apparent in the first few ...