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  2. Ibuprofen - Wikipedia

    en.wikipedia.org/wiki/Ibuprofen

    Ibuprofen. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, fever, and inflammation. [8] This includes painful menstrual periods, migraines, and rheumatoid arthritis. [8] It may also be used to close a patent ductus arteriosus in a premature baby. [9][8] It can be taken orally (by mouth) or intravenously. [8]

  3. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    When nonselective COX-1/COX-2 inhibitors (such as aspirin, ibuprofen, and naproxen) lower stomach prostaglandin levels, ulcers of the stomach or duodenum and internal bleeding can result. [126] The discovery of COX-2 led to research to the development of selective COX-2 inhibiting drugs that do not cause gastric problems characteristic of older ...

  4. Mechanism of action of aspirin - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_action_of_aspirin

    Aspirin acts as an acetylating agent where an acetyl group is covalently attached to a serine residue in the active site of the COX enzyme. [1] This makes aspirin different from other NSAIDs (such as diclofenac and ibuprofen), which are reversible inhibitors; aspirin creates an allosteric change in the structure of the COX enzyme. [2]

  5. Analgesic - Wikipedia

    en.wikipedia.org/wiki/Analgesic

    Nonsteroidal anti-inflammatory drugs (usually abbreviated to NSAIDs), are a drug class that groups together drugs that decrease pain [10] and lower fever, and, in higher doses, decrease inflammation. [11] The most prominent members of this group of drugs, aspirin, ibuprofen and naproxen, Diclofenac are all available over the counter in most ...

  6. Aspirin - Wikipedia

    en.wikipedia.org/wiki/Aspirin

    Aspirin is also used long-term to help prevent further heart attacks, ischaemic strokes, and blood clots in people at high risk. [10] For pain or fever, effects typically begin within 30 minutes. [10] Aspirin works similarly to other NSAIDs but also suppresses the normal functioning of platelets. [10] One common adverse effect is an upset ...

  7. Aspirin-exacerbated respiratory disease - Wikipedia

    en.wikipedia.org/wiki/Aspirin-exacerbated...

    Aspirin-exacerbated respiratory disease (AERD), also called NSAID-exacerbated respiratory disease (N-ERD) or historically aspirin-induced asthma and Samter's Triad, is a long-term disease defined by three simultaneous symptoms: asthma, chronic rhinosinusitis with nasal polyps, and intolerance of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs).

  8. Antipyretic - Wikipedia

    en.wikipedia.org/wiki/Antipyretic

    Antipyretic. Tablets of ibuprofen, a common antipyretic. An antipyretic (/ ˌæntipaɪˈrɛtɪk /, from anti- 'against' and pyretic 'feverish') is a substance that reduces fever. [1] Antipyretics cause the hypothalamus to override a prostaglandin -induced increase in temperature. [citation needed] The body then works to lower the temperature ...

  9. Anti-inflammatory - Wikipedia

    en.wikipedia.org/wiki/Anti-inflammatory

    Anti-inflammatory or antiphlogistic is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics. These drugs remedy pain by reducing inflammation as opposed to opioids, which affect the central nervous system to block pain signaling ...