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The effects established so far for recreational use of ecstasy lie in the range of moderate to severe effects for serotonin transporter reduction. [ 91 ] Impairments in multiple aspects of cognition, including attention, learning, memory, visual processing , and sleep, have been found in regular MDMA users.
Severe dopaminergic neurotoxicity in primates after a common recreational dose regimen of MDMA [nb 1] ("ecstasy")", [1] is an article by George A. Ricaurte that was published in September 2002 in the peer-reviewed journal Science, one of the world's top academic journals.
MDMA (ecstasy) is a popular club drug in the rave and electronic dance music scenes and in nightclubs.It is known under many nicknames, including "e" and "Molly". MDMA is often considered the drug of choice within the rave culture and is also used at clubs, festivals, house parties and free parties. [8]
para-Methoxyamphetamine (PMA), also known as 4-methoxyamphetamine (4-MA), is a designer drug of the amphetamine class with serotonergic effects. [2] [3] [4] Unlike other similar drugs of this family, PMA does not produce stimulant, euphoriant, or entactogen effects, [5] and behaves more like an antidepressant in comparison, [6] though it does have some psychedelic properties.
Ecstasy: Prospective memory performance is sensitive to regular and even moderate ecstasy use. [55] Ecstasy users experience generalized difficulties with prospective memory [2] Methamphetamine is a highly abused drug known commonly as "crystal meth" and chronic use is known to cause cognitive impairment. [56] [2] The same researchers studying ...
Dextromethorphan's effects have been divided into four plateaus. [14] The first plateau (1.5 to 2.5 mg per kg body weight) is described as having euphoria, auditory changes, mild stimulation, and change in perception of gravity. The second plateau (2.5 to 7.5 mg/kg) causes intense euphoria, vivid imagination, and closed-eye hallucinations.
For example, in an MDMA ("ecstasy" and "molly") comedown, if the user experiences severe, persisting emotional distress, such as panic attacks, severe generalized anxiety, or insomnia following an MDMA session, a physician may prescribe a benzodiazepine (specifically, lorazepam) and/or sleep aid (e.g., zolpidem), to alleviate those effects. [3]
Because the use of drugs, including alcohol, is commonly presented as an excuse for risky or socially unacceptable behavior, it is necessary to treat the idea of a direct causal relation between drug use and unsafe sex with caution. Drugs may provide a socially acceptable excuse for engaging in sexual behaviors in which people may want to ...