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The pancreas is an organ of the digestive system and endocrine system of vertebrates. In humans, it is located in the abdomen behind the stomach and functions as a gland. The pancreas is a mixed or heterocrine gland, i.e., it has both an endocrine and a digestive exocrine function. [2] 99% of the pancreas is exocrine and 1% is endocrine.
The exocrine pancreas is one of two compartments that include digestive-acting acinar cells and duct cells.They represent an extension of the intercalated duct into each pancreatic acinus. [1] These cells are commonly known as duct cells, and secrete an aqueous bicarbonate solution under stimulation by the hormone secretin. They also secrete ...
An exocrine pancreas cell is a pancreatic cell that produces enzymes that are secreted into the small intestine. These enzymes help digest food by releasing enzymes as it passes through the gastrointestinal tract. These include acinar cells, which secrete bicarbonate solution and mucin
Exocrine pancreas: pancreas: serous tubulo-acinar 13 Gastric chief cell, Wasmann's glands stomach: serous 14 Glomus coccygeum, coccygeal gland, Luschka's gland or gangliona coccyx, near the tip 15 Goblet cells: digestive tract, respiratory tract: mucous simple unicellular 16 Henle's glands: eyelids, in the conjunctiva: tubular 17 Krause's glands
For example, Pancreas is a classic example of a heterocrine gland with distinct endocrine and exocrine regions. Regulation: Heterocrine glands are subject to intricate regulation, ensuring precise control over the secretion of hormones and other secretory products.
The liver and pancreas are both exocrine and endocrine glands; they are exocrine glands because they secrete products—bile and pancreatic juice—into the gastrointestinal tract through a series of ducts, and endocrine because they secrete other substances directly into the bloodstream. Exocrine sweat glands are part of the integumentary ...
PaSCs are located within the peri-acinar spaces of the pancreas and extrude long cytoplasmic processes that surround the base of the acinus. [2] PaSCs compose 4% of the total cell mass in the gland [4] Stellate cells derive their name from their star shape and are located in other organs such as the kidney and lungs. [2]
There are about 1 million islets distributed throughout the pancreas of a healthy adult human. While islets vary in size, the average diameter is about 0.2 mm. [5]:928 Each islet is separated from the surrounding pancreatic tissue by a thin, fibrous, connective tissue capsule which is continuous with the fibrous connective tissue that is interwoven throughout the rest of the pancreas.