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Roth's spots, also known as Litten spots or the Litten sign, [1] are non-specific red lesions with white or pale centres, seen on the retina of the eye and although traditionally associated with infective endocarditis, can occur in a number of other conditions including hypertension, diabetes, collagen vascular disease, extreme hypoxia, leukemia and HIV.
A major cause of Bitot's spots is vitamin A deficiency (VAD). [4] Rarely, pellagra due to deficiency of vitamin B 3 (niacin) may also cause Bitot's spots. [5] They can also be caused by Colestyramine , which is a bile acid sequestrant which can reduce the absorption of fat soluble vitamins (Vitamins A, D, E, K)
Other signs of endocarditis include Roth's spots and Janeway lesions. The latter, which also occur on the palms and soles, can be differentiated from Osler's nodes because they are non-tender. The latter, which also occur on the palms and soles, can be differentiated from Osler's nodes because they are non-tender.
Some rosacea treatments such as Soolantra, which contains topical ivermectin, can improve rosacea symptoms. The gut-skin connection Much research is centered on better understanding the connection ...
It’s common to get dry patches on your face, but this can be a sign of an underlying health issue. Here’s what you need to know, plus how to get rid of them.
Sun spots, melasma and post-inflammatory hyperpigmentation are common types of skin discoloration that occur when excess melanin — the pigment that gives skin its color — is produced.
Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair.
Brushfield spots are small, white or greyish/brown spots on the periphery of the iris in the human eye due to aggregation of connective tissue, a normal constituent of the iris stroma. The spots are named after the physician Thomas Brushfield , who first described them in his 1924 M.D. thesis.