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Δ 9-tetrahydrocannabinol (THC) Cannabis sativa, scientific drawing from c. 1900 Although the main psychoactive constituent of Cannabis is tetrahydrocannabinol (THC), the plant is known to contain more than 500 compounds, among them at least 113 cannabinoids ; however, most of these "minor" cannabinoids are only produced in trace amounts. [ 10 ]
Female cannabis plants contain at least 113 cannabinoids, [55] including cannabidiol (CBD), thought to be the major anticonvulsant that helps people with multiple sclerosis, [56] and cannabichromene (CBC), an anti-inflammatory which may contribute to the pain-killing effect of cannabis.
Medical cannabis (or medical marijuana) refers to the use of cannabis and its constituent cannabinoids, in an effort to treat disease or improve symptoms. Cannabis is used to reduce nausea and vomiting during chemotherapy , to improve appetite in people with HIV/AIDS , and to treat chronic pain and muscle spasms .
Cannabis plants vary widely, with different strains producing dynamic balances of cannabinoids (THC, CBD, etc.) and yielding markedly different effects. Popular strains are often hybrids of C. sativa and C. indica. The medicinal effects of cannabis are widely studied, and are active topics of research both at universities and private research ...
The bracts surrounding a cluster of Cannabis sativa flowers are coated with cannabinoid-laden trichomes. Cannabis indica plant The classical cannabinoids are concentrated in a viscous resin produced in structures known as glandular trichomes .
Nabiximols (brand name Sativex), an oromucosal spray made of a complex botanical mixture containing cannabidiol (CBD), delta-9-tetrahydrocannabinol (THC), and additional cannabinoid and non-cannabinoid constituents from cannabis sativa plants, was approved by Health Canada in 2005, to treat central neuropathic pain in multiple sclerosis, and in ...
Most people 50 and older who use cannabis do so at least once a month, saying it helps them sleep and eases pain, a new survey found. More than 20% of older adults have used pot in the past year ...
Cannabis use disorder is defined in the fifth revision of the Diagnostic and Statistical Manual of Mental Disorders as a condition requiring treatment. [107] Several drugs have been investigated in an attempt to ameliorate the symptoms of stopping cannabis use. Such drugs include bupropion, divalproex, nefazodone, lofexidine, and dronabinol.